An Autonomous Agent

exploring the noosphere

Category: hemp (Page 1 of 2)

Endocannabinoid System

Posted here are three great lectures on cannabinoids and the Endocannabinoid System in the human body. The first lecture, by Dr. Robert Melamede is my favorite. Melamede frequently references Ilya Prigogine’s work and provides an understanding of the Endocannabinoid system based on a “far from equilibrium” perspective. For the more physics and math inclined readers, this is a wonderful connection.

Dr. Robert Melamede – Endocannabinoid System

 
The Endocannabinoid System in Health and Disease – Dr. Ethan Russo

Quick summary:

  • Endocannabinoid System composed of three components: 1) endocannabinoids, 2) CB1, CB2 and TRPV1 receptors, and 3) regulatory enzymes
  • CB1 is the most abundant G-protein-coupled receptor in the brain
  • Cannabinoids modulate how fast things move through the gut!
  • CB1 is the “psychoactive receptor” and CB2 is the immunomodulatory receptor
  • CBs 10-fold more potent than morphine in WDR neurons mediating pain
  • All humans have a baseline Endocannabinoid System, influenced by genetics or some life event; in some people the system becomes deficient – disease and other issues arise in the body
  • Clinical Endocannabinoid Deficiency (CED)
  • THC notoriously increases appetite, why aren’t users more often obese? THC alters the microfloral balance in gut, prevents weight gain
  • Cannabis very effective in Fibromyalgia
  • Migraine info at 41 min
  • Migraine related to CED

Cannabis and Cannabinoids – Dr. Jeffrey Hergenrather

Quick summary:

  • Compared to the flower: oils, edibles and other extracts lose many of the cannabinoids and terpenes
  • Cannabis is an adaptogen – can give you whatever your body needs to regain its homeostasis
  • CBDs with THC works optimally, together it gives a greater than additive effect, i.e. better than consuming each individually; plant flower and all it contains is overall better than the extracts
  • At 1 hour and 2 min in the lecture, entire list of cancers which exhibit cannabinoid sensitivity and in many cases the tumor goes away with cannabinoid treatment

Marijuana Reconsidered – Lester Grinspoon

For a remarkable and insightful book on cannabis sativa, I would suggest reading Marijuana Reconsidered by Lester Grinspoon. The book provided the first real scientific investigation into the psychedelic properties of cannabis sativa. I found the section by Mr. X (Carl Sagan) to be informative, accurate, and humorous. The fact that marijuana was documented, by William Osler, long before the 1930’s to be the most effective cure for a migraine was a complete surprise to me. I highly recommend this book and any other by Lester Grinspoon.

Volcano Vaporizer

Created by the German company Storz and Bickel, the Volcano Vaporizer is the best on the market.  Highly recommend for anyone wishing to aromatically flavour their food.

Hemp Hoodlamb Tech 4-20 Jacket

Hemp Hoodlamb Tech 4-20 Jacket.  Such a great jacket. Very warm and comfortable. About ten pockets that I can find, including two with magnetic buttons. Made from hemp and recycled plastic, it has a strong and durable feel. Highly recommended as a quality jacket, worth every penny, that will last many years. Might be cheaper here.

The Natural Mind: An Investigation of Drugs and the Higher Consciousness – Andrew Weil, M.D.

In America there exists a large population of people who lack an adequate education on drugs.  The evidence for this conclusion lies in the government’s miss-classification of various drugs, people’s acceptance of prescription drugs, and the fact that the public education system actually spreads drug ignorance. For an introduction to the whole issue I would recommend reading Dr. Andrew Weil’s book, The Natural Mind: An Investigation of Drugs and the Higher Consciousness.

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